The Desus and Mero breakup sounds like it was a pretty long time coming
The Kid Mero says that the Bodega Boys had conflicts going back to 2017

Ever since Showtime announced in July that not only had Desus & Mero come to an end but that Desus Nice and The Kid Mero were going their separate ways altogether, fans haven’t stopped speculating about what caused the Bodega Boys’ split. The Bronx-born duo’s rise from Twitter popularity to podcasting to hosting shows on Viceland and Showtime marked a new path to success made possible by the internet, and the breakup came as a significant blow to longtime followers.
In an interview with Blackbird Spyplane, Mero (aka Joel Martinez) offers up more details about what went down but also hints at deeper problems that have yet to be revealed. Some of the conversation is off the record, thanks to “Media-Training Mero,” and is recapped as “several minutes of candid talk about frustrations with Showtime executives and about fissures in his relationship with Desus going back to 2017" by the fashion newsletter. However, the comedian does clarify the duo’s terms with the network.