Read This: Let science explain why people can’t pick up Thor’s hammer
To fans of Marvel Comics, the answer to the question, “how come only Thor can lift his hammer?” is “actually, whoever is worthy can lift it” (especially this guy), but also “magic.” The Marvel Cinematic Universe, however, is one that conflates magic and science as basically the same thing, opening up how Mjolnir bestows its worthiness to explanation in (highly theoretical) real-world terms. Physicist Jim Kakalios, writing for Wired, explains:
Most likely [the hammer] is taking some complex biological and psychological profile that calculates the “worthiness” of whoever is trying to lift the hammer. This is consistent with the scene in the clip where Steve Rogers (Captain America) is able to move the hammer (albeit slightly), while Tony Stark and Jim Rhodes, using thruster-assisted Iron Man and Iron Patriot gloves, are unable to budge Mjolnir at all.