Thomas Middleditch is taking a break from his comedy tour with Ben Schwartz to once again bless our television screens with his presence (give or take a few phone ads). According to THR, the former Silicon Valley star will headline B Positive, a new sitcom pilot from CBS and TV mastermind Chuck Lorre. Middleditch, who is reportedly one of the most coveted actors this TV pilot season, will star as Drew, a newly-divorced dad in need of a new kidney. Drew’s search leads him to Gina, a “rough-around-the-edges woman” (whatever that means) from his past. She offers him a kidney and the two form a (presumably) hilarious odd coupling as they embark on a life-changing journey together. Described as “Educated, bookish and neurotic,” Drew is a therapist who “lacks social skills and isn’t much of a people person”—so Middleditch is definitely playing in familiar territory.