Kirby would have returned to Scream sooner, but Hayden Panettiere was M.I.A.
"We couldn’t find her," executive producer Kevin Williamson says. "She doesn’t have an agent. She had sort of disappeared."

One of the most exciting reveals in the new Scream 6 trailer that dropped today has to be a first glimpse at the franchise return of Kirby Reed (Hayden Panettiere). A Scream 4 fan favorite and one of the growing collective of women who have survived their dalliances with Ghostface, Kirby (and Panettiere) seem more than primed for a comeback.
That was always the plan, though. In fact, Scream 6 executive producer Kevin Williamson says she would have been back sooner, but the production team just couldn’t seem to locate Panettiere.
“We’re like, ‘Where’s Kirby?’ We couldn’t find her,” Williamson, who wrote Scream 4 (as well as the 1996 original and its sequel), recalls in a new interview with Variety. “She doesn’t have an agent. She had sort of disappeared.”