3. The two Harriet Winslows on Family Matters

It's tough to describe JoMarie Payton-France's absence from Family Matters as jarring, because nobody was really watching Family Matters by the time she was replaced by Judyann Elder. Urkel was still the focus of the show, the sassy Grandma was gone, and mysterious daughter Judy went up the stairs years earlier and never came back. (The actress who played her went on to porn and Celebrity Rehab.) But Payton, who originated the Harriet character on Perfect Strangers, went on to bit parts in other series, taking her husky voice with her.

4. The two Angie Jordans on 30 Rock

Again, this role change was hardly jarring: In the character's first appearance, Tracy Jordan's wife was played—very briefly—by Sharon Wilkins. In all subsequent episodes, she was portrayed by the smiley Sherri Shepherd, who apparently doesn't mind portraying someone who likes to "play rape" with her husband. Good for her!

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5. The two Donnas in Twin Peaks and Twin Peaks: Fire Walk With Me

David Lynch couldn't round up the whole cast for Twin Peaks: Fire Walk With Me,†his big-screen sequel/prequel to the cult-hit TV show Twin Peaks, and he opted to cut characters like Sherilyn Fenn's Audrey instead of recasting them. (Other favorites appeared in scenes that didn't make the final cut, leaving the town of Twin Peaks weirdly underpopulated.) But Lara Flynn Boyle's decision to bail left Lynch with a part he couldn't cut, so he recast her with future Cutting Edge†star Moira Kelly. The film is a confused mess, and Kelly, possibly the least expressive actress of her generation, only makes it messier and more confused.

6. The two young John Connors in Terminator 2 and Terminator 3

Edward Furlong was an unknown when he palled around with Arnold Schwarzenegger's cuddlier killer-from-the-future in Terminator 2: Judgment Day in 1991. He spent the rest of the decade battling personal demons while still taking high-profile roles in films like Pecker†and Detroit Rock City. He was the right age to play an older version of Connor in Terminator 3: Rise Of The Machines, and the character's struggle with drugs seemed to dovetail with Furlong's own experience. Still, Nick Stahl got the part. Not confused enough? A third actor, Thomas Dekker, plays Connor on the TV show Terminator: The Sarah Connor Chronicles,†while no less than Christian Bale has signed on for the part in the McG-directed fourth film, Terminator Salvation, out next year.

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7. The three Gordons on Sesame Street

Childhood memories are easily taintable, so hang on. Gordon wasn't always Gordon. The African-American leader of Sesame Street—especially in its first couple of years—was played by Matt Robinson, who was inexplicably replaced by moustacheless Hal Miller, who looked nothing like Robinson. Miller stayed in the role for a couple of years, until Roscoe Orman took it over in 1974. He holds it to this day.

8. The two Deborah Ciccerones on The Sopranos

This one's more of a tease than a jarring change, because only a certain segment of Sopranos watchers got to see Fairuza Balk play the FBI agent who flips Adriana. According to Balk, the character was only written as a one-off, and when the producers decided to make it bigger, Balk wasn't available. Her scene was re-shot with Lola Glaudini, who would continue in the role.

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9. The two Jennifer Parkers in Back To The Future and its sequels

Claudia Wells debuted the character of Jennifer Parker, Marty McFly's girlfriend, in the original Back To The Future, but dropped out of the sequel released four years later. (Wells wouldn't make another film for more than a decade.) Elisabeth Shue took on the role, which required a re-shoot of the ending of the first film, which became the first scene of Back To The Future II. Shue would reprise the role for Back To The Future III in 1990.

10. The two Gladys Kravitzes from Bewitched

Sure, the two Darrins get all the recognition—probably because Darrin was, y'know, Samantha's husband—but nosy neighbor Gladys Kravitz was replaced after two seasons because the actress who played her, Alice Pearce, died of cancer. Sandra Gould took over the role for the remainder of the series, but never proved to anyone that Samantha was a witch.

11. The two John-Boys on The Waltons

At the end of The Waltons' fifth season, Richard Thomas left the show, and with him went John-Boy, the series' most popular character. At the start of the eighth season, The Waltons' producers brought John-Boy back in an episode that showed him recuperating in a hospital after having his plane shot down in World War II. Only instead of the mole-faced John-Boy audiences knew and loved, the character was played by Robert Wightman. They do say that war changes a man…