Gérard Lanvin (San-Antonio)Gérard Depardieu (Bérurier)Lucy Harrison (La masseuse)Patrick Médioni (Van Gogh)Valeria Golino (L'Italienne)Marc Faure (Son Excellence)Michèle Bernier (Berthe Bérurier)Marie-Thérèse Arène (Félicie)Bill Barclay (L'Écossais)Nick Hobbs (Lord Kensington)Michel Galabru (Achille)Vanessa Guedj (La soubrette)Robert Hossein (Le ministre)Guilhem Pellegrin (Le secrétaire de l'Elysée)Jérémie Renier (Toinet)Elisabeth Margoni (La première dame)Barbara Schulz (Marianne)Richard Chevallier (Le gendarme Elysée)
While a terrorist epidemic strikes the world leaders, the commissaire San-Antonio and his partner Lieutenant Bérurier must escort the French ambassador to a British hotel. But after a negligence of Bérurier (one more little sex affair), San-Antonio powerlessly witnesses the ambassador's abduction, organized by a gorgeous Italian girl. Back in Paris, San-Antonio is dismissed by Police Chief Achille Hachille, which is a real godsend to Bérurier, who gets promoted. But the situation soon degenerates when the president of the Republic mysteriously disappears. Immediate reaction from the Police Minister: only San-Antonio can save the day; he has 48 hours and a secret squad to find the president. At the Elysée, San-Antonio finds Bérurier, the official investigator. But now, it's every man for himself: who will be the first to find the President? There are multiple trails: terrorists, unscrupulous banks, international dealers, dishonest politicians, and pretty women with very convincing arguments.