Brian Keith (Dr. Sean Jamison)Shelley Fabares (Dr. Anne Jamison)Victoria Young (Nurse Puni)Roger Bowen (Dr. Austin Chaffee)Sean Tyler Hall (Stewart)Nancy Kulp (Mrs. Gruber)Michael Gray (Ronnie Collins)Steven Hague (Alfred Landis)Douglas Mossman (Tour Guide)Zulu (Chief Hanamakii)Patricia Herman (Head Nurse)Ronnie Schell (Dr. Victor Lang)Allen Tam (Commissioner)Josephine Pagud (Mrs. Pahali)Sarah Edlin (Mrs. Thrum)Elayne Heilveil (Betty)Phil Vandervort (Jack)Haunani Minn (Joan)
Garry Marshall, Dick Bensfield, Bob Brunner, Jack Elinson, Perry Grant, David P. Harmon, Paul West, Austin Kalish, Irma Kalish, David Ketchum, Michael Leeson, Norman Paul, Bruce Shelly, Jeff Wilhelm, Steve Zacharias, Gerry Renert
In its first season, father and daughter pediatricians, Dr. Sean Jamison and Dr. Anne Jamison, run a free clinic in Oahu, Hawaii. Starting in the second season, very proper Dr. Austin Chaffee shares office space with Dr. Sean Jamison, and finds the easy-going manner of the latter difficult to which to adjust. Mrs. Gruber, the rich widow who owns the clinic, was added to the series in the second season to develop problems that the Jamisons solved.